科研领域描述
本实验室主要兴趣在于：
1 以雄蕊为对象的植物器官形成调控机制
2 植物发育事件相关基因表达在染色质水平调控
植物器官形成主要指来自顶端分生组织的一团未分化细胞如何形成具有特定形态与功能的三维结构，是植物发育中的一个重要过程。我们利用雄蕊为对象，从分析导致黄瓜雌花雄蕊发育停滞的分子机制、和发育早期不同阶段的水稻雄蕊基于表达谱两个角度入手，尝试解析雄蕊早期发育这一复杂的多细胞结构形态建成过程中关键的发育事件及其在分子水平的调控机制。这将不仅帮助我们了解雄蕊形成的机制，还可以帮助我们了解多细胞结构形态建成过程中的一些基本规律。
在我们前期的工作中，发现基因表达的染色质水平调控在植物发育事件中具有重要的作用。因此，我们面前利用拟南芥根表皮细胞分化过程中模式形成这一发育事件，探讨发育相关基因表达在染色质水平的调控机制，并希望利用在此研究中所积累的经验，帮助我们理解雄蕊早期发育的调控机制。
Research Description:
We are focusing on understanding the regulatory mechanisms of PLANT ORGAN-FORMATION, a process that a group of undifferentiated cells in organ primordia elaborate into an organ with particular shape, structure and function, at molecular level. Using stamen as a particular organ type, we are currently taking two approaches to the goal. In one approach, we use cucumber female flower development as a model system to ask how an inappropriate stamen is arrested, which is expected to reveal what is required for a normal stamen organ-formation.
The other approach is that we use rice stamen as a target organ for primordial specific gene expression profiling, aiming at identifying genes differentially expressed during early developmental stages as much as possible, for further dissecting the regulatory network.
Our previous work revealed that histone acetylation is involved in pattern formation of Arabidopsis root epidermis. We continue the exploration in this direction as well.
实验室网页: http://www.plantdev.pku.edu.cn/
代表性论文
1. Bai SN, Xu ZH , Cucumber unisexual flowers, sex and sex differentiation , International Review of Cell and Molecular Biology , 2013 , 304, 1-56
2. Liu C, Li LC, Chen WQ, Chen X, Xu ZH, Bai SN , HDA18 Affects Cell Fate in the Arabidopsis Root Epidermis via Histone Acetylation at Four Kinase Genes , Plant Cell , 2013 , 25: 257-269
3. Bai SN, Xu ZH , Bird–nest puzzle: can the study of unisexual flowers such as cucumber solve the problem of plant sex determination? , Protoplasma , 2012 , doi:10.1007/s00709-012-0396-4
4. Gu HT, Wang DH, Li X, He CX, Xu ZH, Bai SN , Characterization of an ethylene inducible, calcium dependent nuclease that is differentially expressed in cucumber flower development , New Phytologist , 2011 , 192:590-600
5. Sun JJ, Li F, Li X, Liu XC, Rao GY, Luo JC, Wang DH, Xu ZH, Bai SN , Why is ethylene involved in selective promotion of female flower development in cucumber? , Plant Signal. Behavior , 2010 , 5 (8): 1052-1056
6. Bai, SN and Xu, ZH , From ethylene promotion of female flowers to ethylene inhibition of stamen development: a review on the study of developmental fate of inappropriate organs in unisexual cucumber flowers , Sci. Sin Vitae , 2010 , 40(6): 469-475
7. Wang DH, Li F, Duan QH, Han T, Xu ZH, Bai SN , Ethylene perception is involved in female cucumber flower development , Plant J , 2010 , 61：862-872
8. Duan QH, Wang HD, Xu ZH, Bai SN , Stamen development in Arabidopsis is arrested by organ-specific overexpression of a cucumber ethylene synthesis gene CsACO2 , Planta , 2008 , 228 (4): 537-543
9. Lu XC, He Y, Chen M, Tian SL, Bai SN , Photoperiodic responses of various morphogenetic events after panicle initiation in late japonica rice (Oryza sativa L. vs. japonica). , Plant Biology , 2008 , 10: 388-397
10. Peng YB, Zou C, Wang HD, Gong HQ, Xu ZH, Bai SN , Preferential localization of abscisic acid in primordial and nursing cells of reproductive organs of Arabidopsis and cucumber , New Phytologist , 2006 , 170: 459-466
11. Lu XC, Gong HQ, Huang ML, Bai SL, He YB, Mao XZ, Geng Z, Li SG, Wei LP, Yuwen JS, Xu ZH, Bai SN , Molecular analysis of early rice stamen development using organ-specific gene expression profiling , Plant Mol. Biol. , 2006 , 61: 845-861
12. Xu CR, Liu C, Wang YL, Li LC, Chen WQ, Xu ZH, Bai SN , Histone acetylation affects expression of cellular patterning genes in the Arabidopsis root epidermis , PNAS , 2005 , 102: 14469-14474
13. Bai SL, Peng YB, Cui JX, Gu HT, Xu LY, Li YQ, Xu ZH, Bai SN , Developmental analyses reveal early arrests of the spore-bearing parts of reproductive organs in unisexual flowers of cucumber (Cucumis sativus L.) , Planta , 2004 , 220 (2): 230-240
14. Hao YJ, Wang Dh, Peng YB, Bai SL, Xu LY, Li YQ, Xu ZH, Bai SN , DNA damage in early primordial anther is closely correlated with the stamen arrest in female flower of cucumber (Cucumis sativus L.) , Planta , 2003 , 217(6): 888-95
15. Liang YK, Wang Y, Zhang Y, Li SG, Lu XC, Li H, Zou C, Xu ZH, Bai SN , OsSET1, a novel SET-domain containing gene from rice , J. Exp. Bot. , 2003 , 54: 1995-1996
16. Bai SN. and Tan KH , Does the leaf-derived signal generated in photoperiod has specific effects on particular morphologenetic events occurred in shoot apex? ---- Reconsideration of the research on the photoperiodic sensitive genic male sterile rice. , Chinese Science Bulletin , 2001 , 46: 788-792
17. Lu WL. Bai SN. Zhang XS , The exogenous hormonal control of the development of regenerated flower buds in Hyacinthus orientalis , Act. Bot. Sin. , 2000 , 42: 996-1002
18. Bai, SN , Phenomena, interpretation of the phenomena and the developmental unit in plants , in Advances of Botany Vol II, ed. Li, Chengshen , 1999 , 52-69
19. Yang LL., Chen M. Liu FQ. Geng Y, Chen C, Li YQ, Cao ZX., Xu ZH. and Bai SN , Carpel of cucumber (Cucumis sativus. L) male flowers maintains early primordia characteristics during organ development , Chinese Science Bulletin , 1999 , 44(23): 2509-2513
20. Bai SN and Sung ZR , The role of EMF1 in regulating the vegetative and reproductive transition in Arabidopsis thaliana (Brassicaeae) , Am. J. Bot. , 1995 , 82(9):1095-1103
21. Sung ZR, Belachew A, Bai SN and Bertrand Garcia, R. , EMF, an Arabidopsis gene required for vegetative shoot development , Science , 1992 , 258: 1645-1647
22. Bai SN and Xiao YH , Study on the root growth and respiration of hybrid rice , Acta Agronomica sinica , 1988 , 14(1): 57-64 |
