科研领域描述
本实验室主要兴趣在于：
1. 衰老及退行性病变等细胞增殖异常模型中相关蛋白质群及其调控网络研究
2. 神经细胞核蛋白质的动态修饰与功能研究
3. 体内外蛋白质动态修饰与功能研究
代表性论文
1. Wang Q, He J, Meng L, Liu Y, Pu H, Ji J , A Proteomics Analysis of Rat Liver Membrane Skeletons: The Investigation of Actin- and Cytokeratin-Based Protein Components , J Proteome Res , 2009 , May 8. [Epub ahead of print]
2. Liu Y, He J, Wang Q, Ji S, Pu H, Jiang T, Meng L, Yang X, Ji J , Comparative studies of early liver dysfunction in senescence-accelerated mouse using mitochondrial proteomics approaches , Mol Cell Proteomics , 2008 , 7: 1755-1762.
3. He J, Liu Y, He S, Wang Q, Pu H and Ji J, , Proteomic analysis of a membrane skeleton fraction from human liver. , Journal of Proteome Research , 2007 , 6: 3509-3518.
4. He J, Liu Y, He S, Wang Q, Pu H, Tong Y and Ji J , Comparison of two-dimensional gel electrophoresis based and shotgun strategies in the study of plasma membrane proteome. , Proteomics-Clinical Application , 2007 , 1: 231-241.
5. Diao W, Chen W, Wu Y, Liu P, Xie X, Li S, Shen P, Ji J , Serum, liver, and kidney proteomic analysis for the alloxan-induced type I diabetic mice after insulin gene transfer of naked plasmid through electroporation. , Protoemics , 2006 , 6: 5837-5845.
6. He S, Wang Q, He J, Pu H, Yang W and Ji J , Proteomic analysis and comparison of the biopsy and autopsy specimen of human brain temporal lobe. , Proteomics , 2006 , 18: 4987-4996.
7. Yang W, Liu P, Liu Y, Wang Q, Tong Y and Ji J , A proteomics profiling of rat pheochromocytoma PC12 cells , Proteomics , 2006 , 10:2982-2990.
8. Chen T, Wang Q, Cui J, Yang W, Shi Q, Ji J and Shen P, 2005. . , Induction of apoptosis in mice liver by microcystin-LR: a combined transcriptomic, proteomic and simulation strategy , Molecular & Cellular Proteomics , 2005 , 4: 958-974.
9. Zhou B, Yang W, Ji J and Ru B , Differential display proteome analysis of PC-12 cells transiently transfected with metallothionein-3 gene , Journal of Proteome Research , 2004 , 3: 126-131.
10. Zhao R, Ji J, Tong Y, Pu H, Ru B , Use of serological proteomic methods to find biomarkers associated with breast cancer , Proteomics , 2003 , 3: 433-439.
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