科研领域描述
光对于植物来说不仅是重要的能量来源，同时也是极其基本和重要的生长信号。我们的研究兴趣是以拟南芥和苔藓为研究对象，探索光对植物生长发育调控的分子机制。我们前期的研究表明，以CULLIN 4 为核心的E3连接酶广泛参与光信号转导的过程，包括与光形态建成的抑制因子COP1-SPA复合体，CSN复合体 (COP9 signalosome, CSN)，CDD (COP10, DDB1 and DET1)复合体的协同作用。目前在此基础上，我们将继续综合运用遗传学、生物化学、分子生物学、细胞生物学、基因组学等不同的实验手段，进一步解析光信号的传导通路。
代表性论文
1. Chen, H., Chen, W., Zhou, J., He, H., Chen, L., Chen, H.,# and Deng, X.W.# , Basic leucine zipper transcription factor OsbZIP16 positively regulates drought resistance in rice. , Plant Science , 2012 , 193-194, 8-17. (# Co-corresponding Authors)
2. Chen, H., He, H., Zou, Y., Chen, W., Yu, R., Liu, X., Yang, Y., Gao, Y-M., Xu, J-L., Fan, L-M., Li, Y., Li, Z-K., Deng, X. W. , Development and application of a set of breeder-friendly SNP markers for genetic analyses and molecular breeding of rice (Oryza sativa L.) , Theor Appl Genet , 2011 , 123: 869–879
3. Chen, H., Huang, X., Gusmaroli, G., Terzaghi, W., Lau, O.S., Yanagawa, Y., Zhang, Y., Li, J., Lee, J.H., Zhu, D., and Deng, X.W. , Arabidopsis CULLIN4-Damaged DNA Binding Protein 1 Interacts with CONSTITUTIVELY PHOTOMORPHOGENIC1-SUPPRESSOR OF PHYA Complexes to Regulate Photomorphogenesis and Flowering Time. , The Plant Cell , 2010 , 22, 108-123.
4. Chen H., Karplus V., Ma H., and Deng X.W. , Plant Biology Research Comes of Age in China. , The Plant Cell , 2006 , 18, 2855-2864.
5. Chen H., Shen Y., Tang X., Yu L., Wang J., Guo L., Zhang Y., Zhang H., Feng S., Strickland E., Zheng N., and Deng X.W. , Arabidopsis CULLIN4 forms an E3 ubiquitin ligase with RBX1 and the CDD complex in mediating light control of development. , The Plant Cell , 2006 , 18, 1991-2004. |
