本实验室主要兴趣在于:
1. 微管相关蛋白与神经细胞的极性构建及人类疾病
2. 分子马达与神经细胞内的物质运输
3. 神经系统发育及细胞分化的分子机制
代表性论文
1. Chen L, Xu S, Liu L, Wen X, Xu Y, Chen J* and Teng J* , Cab45S inhibits the ER stress-induced IRE1-JNK pathway and apoptosis via GRP78/BiP , Cell Death Dis. , 2014 , (accepted)
2. Wang Q, Shen B, Chen L, Zheng P, Feng H, Hao Q, Liu X, Liu L, Xu L, Chen J* and Teng J* , Extracellular Calumenin Suppresses ERK1/2 Signaling and Cell Migration by Protecting Fibulin-1 from MMP-13-mediated Proteolysis , Oncogene , 2014 , (online)
3. Feng H, Chen L, Wang Q, Shen B, Liu L, Zheng P, Xu S, Liu X, Chen J and Teng J* , Calumenin-15 facilitates filopodia formation by promoting TGF-β superfamily cytokine GDF-15 transcription , Cell Death Dis. , 2013 , 4, e870
4. He R, Huang N, Bao Y, Zhou H, Teng J* and Chen J* , LRRC45 Is a Centrosome Linker Component Required for Centrosome Cohesion , Cell Reports , 2013 , 4:1100-1107
5. Wang Q, Shen B, Zheng P, Feng H, Guo Y, Cao W, Chen L, Liu X, Zhao G, Sizheng Xu, Shen W, Chen J* and Teng J* , BmCREC Is an Endoplasmic Reticulum (ER) Resident Protein and Required for ER/Golgi Morphology , J Biol Chem. , 2013 , 288(37):26649-26657
6. He R, Wu Q, Zhou H, Huang N, Chen J* and Teng J* , Cep57 is required for cytokinesis by facilitating central spindle microtubule organization , J Biol Chem. , 2013 , 288(20):14384-14390
7. Miao L, Teng J*, Lin J, Liao X and Chen J* , 14-3-3 Proteins Interact with Neurofilament Protein-L(NF-L) and Regulate Dynamic Assembly of Neurofilaments , J. Cell Sci. , 2013 , 126(Pt2):427-436
8. Liu Y, Lv K, Li Z, Yu Albert CH, Chen J* and Teng J* , PACSIN1, a Tau-interacting protein, regulates axonal elongation and branching by facilitating microtubule instability , J Biol Chem. , 2012 , 287(47):39911-39924
9. Wu Q, He R, Zhou H, Yu Albert CH, Zhang B, Teng J* and Chen J* , Cep57, a NEDD1-binding pericentriolar material component, is essential for spindle pole integrity , Cell Res. , 2012 , 22(9):1390-1401
10. Wang Q, Teng J*, Shen B, Zhang W, Guo Y, Su X, Zhang C, Yu AC and Chen J* , Characterization of Kinesin-like Proteins in Silkworm Posterior Silkgland Cells , Cell Res , 2010 , 20: 713-727
11. Teng J, Tatemitsu R, Yosuke T, Yosuke T, Takao N, Motoyuki H, Ashok BK and Nobutaka H , The KIF3 motor transports N-cadherin and organizes the developing neuroepithelium , Nat Cell Biol , 2005 , 7: 474-482
12. Teng J, Takei Y, Harada A, Nakata T, Chen J and Hirokawa N , Synergistic effects of MAP2 and MAP1B knockout in neuronal migration, dendritic outgrowth, and microtubule organization , J Cell Biol , 2001 , 155: 65-76